Thalassemia below 60g/L requires blood transfusion. Thalassemia is a class of autosomal recessive genetic diseases with disorders of pearl protein synthesis, which is classified into severe thalassemia, intermediate thalassemia and mild thalassemia according to the severity of the disease. 1. Thalassemia of mild type does not need special treatment and will not affect your life. 2. Patients with thalassemia major need lifelong blood transfusion and iron removal therapy to maintain hemoglobin at 60~80g/L to maintain physiological functions. Drugs include Deferasirox, etc. Hemoglobin of 60g/L has indicated the development of severe anemia, accompanied by hemolysis, combined with severe infections, anemic heart failure, etc., which are all indications for blood transfusion. If thalassemia is lower than 60g/L, it is recommended to go to the hospital in time for regular treatment under the guidance of a physician.