As our unit has been committed to the research of cranial 3D prediction, we were invited to participate in the conference of 3D simulation held in San Francisco, USA, and saw the prospect of widely application of this advanced technology in dental clinic with the combination of computer and “cone beam CT (CBCT)”, and it can bring more prediction for clinicians and patients. It can bring more diagnostic and treatment outcome prediction to clinicians and patients, and ultimately benefit patients. The 3D technology can be used in the following areas. Prediction of orthodontic posterior shape: Whether a doctor is brilliant or not is, in a sense, the doctor’s foresight. A brilliant doctor has comprehensive and precise foresight and can inform the patient of possible negative results and corresponding treatment measures before treatment, and if there are no treatment measures, he or she should choose this treatment carefully, so the ability to predict is very important in medicine. The traditional prediction in facial and orthodontic treatment is lateral profile prediction, that is, two-dimensional prediction. This prediction method is difficult to accurately see the entire structure of the facial bones because it can only trace the changes in the lateral profile of the patient, and patients and doctors with poor clinical experience often cannot see it. Due to the development of contemporary CT technology, CBCT can acquire clear images with 1/40 (1 in 40) radiometric measurement of conventional CT, and can reconstruct a clear three-dimensional image of the craniofacial structure, and the doctor operates in three dimensions to present the changes of treatment results on the lateral profile jaw front, which greatly improves the doctor’s control over treatment, especially in orthodontics to predict the need for extraction orthodontics, as well as the change pattern of the posterior shape after extraction orthodontics, can guide the treatment plan more precisely.