The treatment of pulmonary and mediastinal lymph node tuberculosis includes medication and surgery, and the use of medication should follow the doctor’s instructions. 1. Drug treatment: regular anti-tuberculosis drug treatment, commonly used drugs include isoniazid, rifampicin, etc., which are used to kill Mycobacterium tuberculosis and reduce the spread of the disease. 2. Surgery: The treatment is lymph node dissection, which aims at removing the enlarged lymph nodes to avoid further aggravation of the disease. Before and after the surgery, a regular, effective and sufficient course of anti-tuberculosis medication is needed. If tuberculosis of hilar and mediastinal lymph nodes is diagnosed, it is recommended to go to a regular hospital in time to receive standardized treatment, so as to relieve the symptoms and cure the disease as soon as possible.