The preferred treatment for growth hormone pituitary tumors is transsphenoidal approach adenomectomy. Because patients with growth hormone adenomas are prone to have associated limb hypertrophy, they also lead to hypertrophy of the pharyngeal tissue, causing difficulty in tracheal intubation. To ensure the safety of the procedure, a preoperative tracheotomy may be performed. The surgical results are good for this group of patients with low postoperative complications. If the tumor is large and surgical resection is incomplete or if the growth hormone is still greater than 2ug/L 3-6 months after surgery and the symptoms do not resolve, the patient can be temporarily observed. If the tumor is greater than 10ug/L, radiation therapy is required again. The recurrence rate of growth hormone adenoma after surgery is about 0-13%.