There is no difference in treatment between the presence of warts in the coronary area and the presence of warts in other areas. Physical therapy, topical medications or injections at the base of the warts are generally used to necrolyze the warts. Commonly used physical therapy methods such as laser, freezing, photodynamic; commonly used topical drugs such as tincture of onychomycosis, imiquimod ointment, fluorouracil ointment; commonly used in the warts at the base of the injection is interferon. After the warts fall off, interferon needs to be injected intramuscularly to remove the HPV virus from the body. Patients can take oral Chinese medicine or Western medicine to regulate their own immune resistance. If the patient occurs coronary pearl rash, also known as pseudo condyloma acuminatum, there is no need for treatment.