Pimples near the buttocks may be associated with conditions such as folliculitis, infectious warts and eczema. They can be removed by applying antibiotic drugs, antiviral drugs and taking antihistamines. 1. Folliculitis: Folliculitis causes damage to the subcutaneous nodular tissue and the formation of connective tissue, leading to pimples near the buttocks, with pustules appearing in the center within a few days, surrounded by a red halo. It can be removed by applying antibiotic drugs such as mupirocin ointment and fusidic acid ointment. 2. Infectious warts: a viral transmission disease. It may be related to direct contact transmission, sexual transmission and other factors, which can lead to a long pimple near the patient’s buttocks, which is gray or pearl-colored. Warts can be removed by clamping, or by applying antiviral drugs such as imiquimod cream and cidofovir ointment. 3. Eczema: Inflammation of the superficial dermis and epidermis caused by a variety of internal and external factors. Clinically, acute stage lesions are dominated by pimples with a tendency to ooze, which may cause pimples and papules near the buttocks. Antihistamine drugs such as cetirizine tablets and loratadine tablets can be taken for treatment. Causes of pimples near the buttocks may also be related to urticaria and other causes. All of the above medications should be used as prescribed by the doctor. It is recommended that patients should go to the hospital in a timely manner, under the guidance of the doctor for treatment, do not self-medication.