The absence of fever in HFMD means that the disease is almost over. Because the whole course of HFMD is about 7-10 days, if there is fever, most of them will last for 5-7 days, so after the fever subsides, HFMD is basically cured. Hand, foot and mouth disease can be divided into light and heavy, light mostly accompanied by fever, loss of appetite, and then the rash on the day of fever or the next day, there is a certain degree of contagious, so hand, foot and mouth disease in the antiviral, antipyretic and other symptomatic treatment at the same time, pay attention to the development of good personal hygiene habits, diligent hand washing, pay attention to the isolation and disinfection of utensils and toys, to achieve early detection, early isolation, early treatment.