There are two main reasons for high platelet pressure volume: first, the increase of total platelet count, the total platelet count is elevated, such as infection, blood loss, hemolysis, tumors can make platelets elevated, too high, in the exclusion of other blood disease system, the cause of thrombocytosis must be identified, such as whether the primary or secondary platelet elevation. Secondly, there is another important reason for high platelet pressure, which is the increase in the average platelet volume. The increase in the average platelet volume indicates that the megakaryocytes are highly mature, and the bone marrow is good at making platelets, and there is another important reason for high platelet pressure, which is that vascular contraction also causes high platelet pressure, because platelets are adhered to the endothelium of the blood vessels, when the blood vessels are damaged and contracted, the platelets will react with the glycoproteins on their own surface and the endothelium. When the blood vessel is damaged and contracted, the glycoprotein on the surface of the platelet adheres to the collagen under the endothelium, and the aggregation of platelets with each other makes the platelets accumulate, and the platelet pressure will naturally be elevated.