Chronic renal failure patients with long-term use of dialysis tubing sometimes occurs blockage, once appeared need to be actively treated, otherwise it will affect the patient’s regular dialysis, and lead to a variety of complications. In general, after the discovery of dialysis tubing blockage, urokinase should be used to dissolve the tubing local treatment, if the effect of vascularization can be achieved, can be carried out again dialysis treatment. If after the use of urokinase lysis or repeated repeated dialysis tube blockage, it is necessary to choose a new vascular access for tube placement or choose endovascular fistula.