Glutamine can protect and repair the gastric mucosa, mainly used in the treatment of chronic gastritis, peptic ulcer and other diseases. Glutamine is an amino acid drug, which has a protective and repairing effect on gastrointestinal mucosal damage, and is mainly used in the treatment of chronic gastritis, peptic ulcer and other diseases in clinic, and also used in the nutritional support of critically ill patients. Adverse reactions such as epigastric pain, stomach upset, vomiting, nausea, diarrhea, constipation, thirst, facial erythema rash, and flushing of the face may occur when taking glutamine. It should be contraindicated in patients with severe liver disease and those who are allergic to the product, and should be used with caution in children, the elderly, pregnant and lactating women. During the period of administration, attention should be paid to increase the intake of food with high fiber content and drink more water to avoid constipation. When taking glutamine, it is recommended to consult a doctor in advance and take it in strict accordance with the doctor’s instructions, not self-medication to avoid delay or even aggravate the condition.