Gray nail middle rotten empty can choose general treatment, drug treatment, surgical treatment and other ways. 1. General treatment: patients should pay attention to personal hygiene during the treatment period, wash hands in time after contacting the affected area to avoid cross-infection. 2. Drug treatment: gray nails in the middle of the rotten empty is due to fungal infection, treatment can be oral antifungal drugs, such as itraconazole, terbinafine, etc., can be appropriate topical amorphophallus powder and other antifungal drugs, you should adhere to the use of medication. 3. Surgical treatment: If the gray nails in the middle of the rotten hollow is more serious, the effect of drug treatment is not obvious, then you can choose surgical treatment, through the surgery to pull out the nails. After the appearance of gray nails in the middle of the rotten hollow, it is recommended that patients go to the hospital in a timely manner, follow the doctor’s instructions to use the above medication, do not use indiscriminately, so as not to lead to adverse consequences.