Systemic lupus erythematosus is an autoimmune-mediated, diffuse connective tissue disease with immune inflammation as the prominent manifestation. It is most commonly seen in females and rarely in males in the age group of 15-45 years. It can present with a variety of clinical manifestations such as arthritis, rash, fever, hair loss, oral ulcers, and even damage to the heart, brain, kidney, blood, gastrointestinal system. The clinical manifestations are diverse. It is a serious threat to human health. At present, lupus cannot be cured. Like rheumatoid arthritis, the disease can be controlled and the damage to organ tissues can be reduced. Long-term medication is needed, and during the stabilization period, it is also necessary to gradually reduce the medication under the guidance of a professional doctor, and not to stop it at will to prevent the disease from recurring. For the treatment is not too much description, mainly about the daily precautions. 1, avoid sunlight exposure: ultraviolet radiation can easily induce the appearance of rashes, leading to the recurrence of disease. It is best to take an umbrella with you when you go out on a sunny day, especially at noon when the UV intensity is high. 2. Avoid using irritating cosmetics, don’t tattoo your eyebrows, dye your hair: some information shows that these chemical elements, when in contact with human skin, can induce an immune response in the body, leading to the occurrence of autoimmune diseases. It may induce lupus and even aggravate the disease. Try not to use cosmetics. If you use it, choose natural and non-irritating cosmetics. 3, do not overwork: appropriate exercise can improve the body’s immunity, too much exercise but make the body immune decline, causing disease relapse. And the chances of infection increase. Staying up late and prolonged exposure to the computer and television screen may also lead to the recurrence of the disease. The good sleep and good attitude are conducive to the recovery and stability of the disease. There is no impact on married life, pay attention to physical hygiene, do not strain on it. 4, avoid excessive spicy stimulating food and allergic food: generally the same as the normal human diet. Do not need to worry too much. 5, as far as possible to quit smoking: cigarettes may aggravate the disease. Avoid excessive alcohol consumption and limit the amount of alcohol consumed. 6, timely medical care: when there are changes in the condition should be timely medical care, early treatment can better control the disease. If you have fertility requirements, you should inform your doctor in advance and adjust your medication according to your condition, refer to the fertility chapter for rheumatism patients.