Retroperitoneal mesenteric root lymphoma is a malignant tumor occurring in lymph nodes or lymphatic tissues of mesenteric root, which manifests as local symptoms caused by enlarged lymph nodes in mesenteric root and systemic symptoms secondary to malignant tumor. 1. Local symptoms: early asymptomatic, most of the health checkups found that there are enlarged lymph nodes in the abdominal cavity, and gradually appear abdominal pain and discomfort, lymph node enlargement may lead to intestinal obstruction and acute peritonitis. 2. Systemic symptoms: before the discovery of enlarged lymph nodes, patients usually have fever, night sweating and emaciation, etc. Some patients will have skin erythema, blisters, even erosion, the skin breakage will not be healed for a long time, and the elevation of leukocytes in routine blood test is obvious. The main method of mesenteric lymphoma treatment is systemic chemotherapy, and if complicated with acute peritonitis such as intestinal obstruction and intestinal perforation, surgery is needed. Abdominal discomfort, it is recommended to consult a doctor in time, standardized treatment under the guidance of a professional doctor, so as not to delay the condition.