Large acne may be the emergence of folliculitis, acne and other diseases, generally can be eliminated through conservative treatment, drug treatment, surgical treatment and other methods. 1. Folliculitis, patients with large acne may be suffering from folliculitis, you can use medication under the guidance of a doctor, such as oral doxycycline, minocycline, etc., but also with topical ointment treatment, such as erythromycin ointment, mupirocin ointment and so on. 2. acne, may also be the emergence of acne, need to be under the guidance of the doctor can be used isotretinoin soft capsule and other medication, with the external use of clindamycin metronidazole cream, benzoyl peroxide cream and so on. Usually need to pay attention to personal skin care, keep the skin clean and moisturized, pay more attention to rest, ensure sufficient sleep.