Many adult female migraine patients have the experience that after taking oral contraceptives, their headaches become more severe and the frequency of attacks increases considerably. It turns out that birth control pills are designed to inhibit ovulation or egg laying by regulating estrogen and progesterone in the body. Migraine patients already have an imbalance in the ratio of estrogen, and taking oral contraceptives can aggravate this result. As a result, the headache becomes more frequent. Sometimes, even women who do not have headaches can have headaches. Therefore, women with hypertension, thrombophilia or migraine, especially those over 35 years of age, should avoid taking oral contraceptives and use other contraceptives instead.