Irbesartan hydrochlorothiazide can be taken once a day, some patients can take twice a day. Irbesartan Hydrochlorothiazide belongs to the compound preparation, the main indication is hypertension, with vasodilatory and diuretic effects, especially suitable for the treatment of hypertension with cardiac insufficiency, water and sodium retention patients. Most patients can take oral Irbesartan Hydrochlorothiazide once a day, which can keep the blood pressure stable. For some patients with more severe conditions, such as hypertension with severe edema and high blood pressure levels, Irbesartan Hydrochlorothiazide can be taken twice a day for treatment. Adverse reactions such as dizziness and nausea may occur with the use of this drug, which is not recommended for patients with severe liver and kidney impairment. Clinically, the usage and dosage of Irbesartan Hydrochlorothiazide should be selected according to the specific condition, and the treatment program should be adjusted under the guidance of the physician.