Folliculitis on the buttocks is an infectious skin disease caused by Staphylococcus aureus and Streptococcus epidermidis infecting the hair follicles and the tissues surrounding the hair follicles. In terms of treatment, topical antibiotic ointments such as erythromycin ointment, fusidic acid cream, and Bactrim cream can be given. If the condition is more serious, it can be treated with oral antibiotics such as roxithromycin capsules, amoxicillin capsules or cefixime tablets. The specific diagnosis and treatment is recommended to give reasonable treatment after the clinician makes a clear diagnosis to avoid delaying the condition.