Pain in the front bone of the calf after running is treated according to the cause, and common causes include osteochondritis dissecans, sports injuries and tibial tuberosity. Treatment includes rest and braking, physical therapy, medication and surgery. 1. Osteochondritis Dissecans: Bone pain caused by osteochondritis dissecans can be treated with rest and braking, local topical application of ointment and moxibustion, and when the pain is severe, non-steroidal anti-inflammatory drugs such as ibuprofen and aspirin can be used to reduce inflammation and relieve pain. 2. Sports injuries: sports injuries caused by bone pain should immediately stop sports, pay attention to rest, but also can be used locally to activate blood circulation and eliminate blood stasis drugs such as Yunnan Baiyao, panax ginseng tablets, etc. to improve the symptoms. 3. Tibial tuberculosis: usually due to a large number of sports caused by local aseptic inflammation. At this time to reduce the amount of exercise, local use of anti-inflammatory drugs such as acetaminophen, celecoxib and other relief. There may be other reasons for the pain in the front bone of the calf after running, such as tumors, etc. When there is prolonged pain that cannot be relieved, it is recommended to consult a doctor in a timely manner, and the above medications should be used in a standardized and reasonable manner under the guidance of a professional physician and pharmacist.