The main side effects of the new coronavirus vaccine include local adverse reactions, systemic adverse reactions and serious adverse reactions. 1. Local adverse reactions: mainly include local reactions such as pain, hardness, redness, swelling and itching at the vaccination site, which generally do not require special treatment and will be relieved in 2~3 days. 2. Systemic adverse reactions: such as fever, headache, fatigue, diarrhea, nausea, vomiting, loss of appetite, etc., usually pay more attention to diet and rest, usually 1~3 days can be relieved. 3. Serious adverse reactions: mainly including anaphylactic shock or syncope, in severe cases, there may be pallor, drop in blood pressure, dizziness, lightheadedness, respiratory difficulties, which may lead to death if not treated in time. After vaccination with the new coronavirus vaccine requires a 30-minute stay to facilitate observation of the vaccinee for any abnormal adverse reactions, and if an acute allergic reaction occurs, treatment can be administered in a timely manner. The precautions to be taken after receiving the new coronavirus vaccine are to eat a light diet, avoid spicy and stimulating foods, pay more attention to rest, avoid overworking the body, do not get the vaccination site wet too soon, and also closely observe the body’s symptomatic manifestations as well as changes in body temperature.