There are many causes of focal bulging of the gastric sinus, including benign lesions and malignant lesions. Focal elevation of the gastric sinus is a term used in endoscopy, and the lesion above the gastric mucosa is called focal elevation of the gastric sinus, which is generally categorized into benign and malignant according to the pathological findings. 1. Benign lesions: including gastric polyps, gastric smooth muscle tumors, gastric lipomas, gastric ectopic pancreas, gastric neuroendocrine tumors, hemangioblastomas, calcified fibrous tumors and so on. 2. Malignant lesions: including malignant lymphoma, gastric cancer, gastric malignant mesenchymal tumor, gastrinoma, liposarcoma and so on. In addition to the above lesions, inflammatory hyperplasia of the gastric sinus, such as congestion and edema of the gastric sinus mucosa, can also be seen in the above manifestations. It is recommended that patients identify the cause of the disease under the guidance of professional physicians and undergo regular treatment.