Sodium citrate is generally referred to as sodium citrate anticoagulant, and the side effect of low blood calcium can occur when used too quickly or in excess, and the exact occurrence varies from person to person. Sodium citrate anticoagulant is an in vitro anticoagulant, which can inhibit the coagulation process and prevent blood coagulation, and is only suitable for use as an in vitro anticoagulant for single raw plasma collection. Direct clinical use of the harvested plasma should be contraindicated. Under normal transfusion rate, the drug will not cause adverse reactions, but when the transfusion rate is too fast or the transfusion volume is too large, it can cause the recipient to suffer from low blood calcium due to the inability of citrate to be oxidized in a timely manner, which can be manifested as convulsions of hands and feet and inhibition of myocardial contraction, and the specific occurrence of the relevant side effects varies from person to person. The specific use of drugs should be carried out under the guidance of specialists, not unauthorized use of drugs.