There is no callus fastest removal, can be removed faster by direct clipping, physical therapy and other methods. Callus, also known as callus, is due to the palm or the bottom of the foot for a long time by extrusion, friction, hyperkeratosis formation of yellowish patches, belong to the skin tissue hyperplasia, accompanied by pain, etc., a serious impact on daily activities, can be used in the following ways to remove the callus: 1. Directly cut off: first of all, use hot water to fully soften the callus, use scissors to carefully cut off the part of keratinized hyperplasia, you can also use a razor blade to carefully scrape off the thickened part of the keratin, and then under the guidance of the doctor to apply the salicylic acid cream, which can play a role in dissolving the keratin. 2. Physical therapy: you can take liquid nitrogen freezing, laser and other direct callus necrosis, carbonization, postoperative application of erythromycin ointment or scalding cream, local use of sterile gauze bandage. If you have symptoms of physical discomfort, you should go to the hospital in time, under the guidance of the physician, give targeted treatment after the cause is clear.