Montelukast and cephalosporin can not be eaten together, because taking at the same time will affect the effectiveness of the drug. Montelukast is an antidiarrheal drug for patients with chronic diarrhea, with adsorption, protection of gastric mucosa and other effects, but need to pay attention to constipation and other adverse reactions. Cephalosporin is an antibiotic drug with anti-inflammatory and bactericidal effects. Before taking cephalosporins, it is necessary to test blood and stool routine, and pay attention to nausea, vomiting and other adverse reactions. It is recommended that patients take montelukast first, at least one hour interval, and then take cephalosporin, for fear that montelukast adsorption of cephalosporin drugs, affecting the efficacy of the cephalosporin drugs, and then delayed the therapeutic effect. The above drugs are recommended to be used under the guidance of a doctor, not blindly self-medication to avoid adverse effects.