Hepatitis B virus e antibody refers to the antibody produced by the body’s immune system in response to the action of the e antigen of the hepatitis B virus on the body. There are three types of hepatitis B virus antigens, e antigen is one of them, and the body’s immune system can produce e antibodies against e antigen. e antibody negativity can be seen in normal people who are not infected with hepatitis B, or in normal people who have been vaccinated against hepatitis B. If the e antigen or e antibody is positive, it is only seen in people who have been infected with hepatitis B. If the e antigen is positive, it is usually a major triplet, which means that the amount of virus replication is high. e antibody is positive, the e antigen will turn negative, which is usually a minor triplet, and the corresponding amount of virus is usually low, which is not absolute and depends on the amount of hepatitis B virus DNA.