High urea nitrogen, uric acid, and creatinine all indicate the presence of hyperuricemia or gout and possible renal insufficiency. Uric acid is the end product of purine metabolism, and blood uric acid >420 μmol/L is usually called hyperuricemia. Urate forms crystals that are deposited in a variety of tissues, including the kidneys and synovium of joints, causing tissue damage. A high uric acid level in a patient indicates the presence of hyperuricemia, and if accompanied by symptoms such as sudden onset of severe pain in one or more joints, the patient may be experiencing gout. Elevated urea nitrogen and creatinine usually indicate renal insufficiency, while high urea nitrogen, uric acid and creatinine may be caused by gouty kidneys leading to renal insufficiency and thus elevated urea nitrogen and creatinine, or renal insufficiency leading to elevated uric acid levels. Urea nitrogen, uric acid, creatinine are high may also have other reasons, it is recommended that patients go to the regular hospital in a timely manner, improve the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.