Long-term, high doses of folic acid will interfere with the metabolism in the body, especially zinc metabolism, leading to zinc deficiency, and zinc deficiency in the mother-to-be not only affects her own health, with decreased immunity, aggravated pregnancy reactions and loss of appetite. More importantly, it affects the growth and development of the baby, which can lead to abnormal metabolism of the baby, such as malnutrition, cardiac insufficiency, fetal malformation, loss of balance of osmotic pressure in the body, and the development of the fetus can become abnormal. Folic acid supplementation should not be taken blindly, and the amount must be controlled.