Thyroid nodules are a common endocrine disease that can be categorized as benign and malignant. Multiple nodules is a kind of thyroid nodules, thyroid nodules multiple nodules are generally benign, single nodules are mostly malignant, nodular thyroid manifested as multiple nodules, medium hard texture, usually with symptoms of hypothyroidism. Subacute thyroiditis caused by viral infection can present as a single nodule or as multiple nodules evolving, and there can be strong positivity for thyroglobulin antibodies. Thyroid nodules can also be examined by ultrasound, as well as nuclear thyroid tests.