High bile acids in infants and young children do not usually affect calcium absorption, but suggest the possibility of neonatal hemolysis, viral hepatitis, and congenital biliary atresia, which need to be taken seriously. Calcium is generally absorbed in the small intestine. If the food is high in oxalic acid or phytic acid, or if the fatty acid level is high in the body, it may affect calcium absorption. This is because acids form insoluble substances with calcium, which in turn leads to a decrease in the amount of absorbable calcium. The normal value of serum total bile acid is 0~10μmol/L. Even if the value of bile acid is high, it will not affect calcium absorption, which generally suggests the existence of neonatal hemolysis, viral hepatitis, and congenital biliary atresia, etc. Generally, infants and young children manifested as persistent jaundice, and need to consult a doctor in a timely manner to find out the cause. Therefore, high bile acid in infants and young children will not affect calcium absorption, but when oxalic acid and phytic acid in food are high, or fatty acids in the body are high, calcium absorption will be affected. High bile acids generally indicate the presence of diseases that may affect bile circulation, and prompt medical treatment is recommended to avoid delaying the best time for treatment.