Bleeding and discharge of blood clots on the 45th day of pregnancy may be due to preeclampsia, biochemical pregnancy, ectopic pregnancy, other factors and so on. 1. Pre-eclampsia: 45 days of pregnancy belongs to the early stage of pregnancy, if it is determined to be an early intrauterine pregnancy, due to the instability of the embryo’s bed, coupled with a number of external factors may lead to pre-eclampsia, resulting in bleeding, clots and so on. 2. Biochemical pregnancy: some girls usually irregular menstrual cycle, sperm and egg combination time is late, there is the possibility of biochemical pregnancy, and biochemical pregnancy can also lead to bleeding, discharge of blood clots phenomenon, the amount of bleeding and the usual amount of menstruation is almost the same. 3. Ectopic pregnancy: for ectopic pregnancy may also have blood clots, accompanied by increased bleeding, severe abdominal pain and other symptoms. 4. Other factors: Besides the above reasons, some women suffer from vaginal or cervical lesions, endocrine disorders, viral infections, improper sexual life, etc., which may also lead to bleeding. When this situation occurs, it is recommended to go to the hospital in time, to carry out the relevant programs for examination, to clarify the specific causes of the disease, and then follow the doctor’s instructions to deal with the treatment.