Smoke at least 24 hours after having a gastroscopy biopsy. Gastroscopy will stimulate the local mucosa, such as stimulation of the mucosa of the throat, foreign body sensation in the throat, edema, etc. Gastroscopy to take a biopsy of the mucosa will lead to wounds in the esophagus or stomach, and the recovery time will be relatively long, so it is generally recommended to smoke again after 24 hours. Cigarettes contain nicotine and other harmful ingredients, the smoke and tar produced during smoking will irritate the patient’s throat and other parts of the body, leading to nausea, vomiting, stomach pain and other symptoms, which is not conducive to the recovery of the organism after gastroscopy, so smoking is not recommended no matter what time of the day. Moreover, tobacco itself is not good for health, so it is recommended to quit smoking. If you have stomach pain, heartburn, acid reflux and other discomforts after a gastroscopy biopsy, it is recommended to return to the hospital as soon as possible and take appropriate measures under the guidance of the doctor.