Most of the headaches are caused by organic lesions, and the common diseases include cranial tumors and central nervous system infections. Patients with cranial tumors generally have a subacute onset, with gradual onset of headache, nausea, vomiting, and also physical symptoms and signs, and cranial MRI should be examined and a clear diagnosis made if necessary. Central nervous system infection includes encephalitis and meningitis, encephalitis is a viral infection and meningitis is a bacterial infection, both of which can cause headache, nausea and vomiting. Patients with encephalitis may generally present with somatic symptoms, and meningitis with signs of meningeal irritation. Both diseases can present with fever, and if necessary, routine blood tests, electroencephalogram, and extraction of cerebrospinal fluid for pathogenic examination should be performed to clarify the diagnosis. Alternatively, it may be caused by extracranial organic disease. Common diseases include paranasal sinusitis, glaucoma, and also dental inflammation, among others. If the patient has a history of hypertension, it may also cause a persistent headache. Tension headache occurs mostly in young adults between the ages of 20 and 30. Patients usually have persistent swelling, aching, and dull pain in the occipital region, frontotemporal region, and the top of the head, and the main manifestation is a feeling of pressure and tightness. Symptomatic treatment is mainly given, and oral ibuprofen, indomethacin and diclofenac can be administered. Physical therapy can also be administered, such as relaxing the patient, reducing stress, improving sleep, etc.