Acid-base imbalance in the vagina should be further checked with routine leukorrhea examination to understand, and then according to the acid-base balance imbalance medication. Female vaginal acid-base imbalance within the vagina, the vaginal cleanliness is reduced, further examination of the leukorrhea routine there is no fungi, trichomonas and other infections, wash the vulva with red nuclear lotion, put lactobacillus vaginal capsule in the vagina, to change the cleanliness and pH value. Female vaginal acid-base imbalance is high pH, the vagina is more alkaline than normal, suitable for the survival of Trichomonas vaginalis, easily triggering trichomonas vaginitis, use Jie Er Yin lotion, metronidazole vaginal effervescent tablets, inhibit Trichomonas vaginalis, so that the vaginal pH is lowered. Female vaginal pH imbalance is low pH, vaginal acidity, suitable for the growth and reproduction of pseudomyces yeast, easily triggered by vulvovaginal pseudomyces yeast infections, with sodium bicarbonate solution wash, bitter ginseng gel, nitrate miconazole suppositories and other medications, so that the vaginal pH to restore the balance. The above drugs are recommended to be used safely under the guidance of a doctor, and an imbalance of acidity and alkalinity in the vagina should be treated in a targeted manner in a hospital.