There are many reasons for high creatine kinase CK, which is affected by gender, age, race and physiological status. Creatine kinase can be categorized into three subtypes, including cardiac muscle type, skeletal muscle type, and brain type, so it is said that any cause of injury to these three areas can cause elevated creatine kinase. 1. such as male creatine kinase activity is higher than female, newborns born with skeletal muscle injury and temporary hypoxia, so that creatine kinase is elevated, black people creatine kinase is higher than white people, after exercise can cause creatine kinase increase. 2. Creatine kinase is one of the sensitive indicators for early diagnosis of myocardial infarction. 3. Myocarditis and muscle diseases: myocarditis can increase creatine kinase, and various muscle diseases such as polymyositis, rhabdomyolysis and progressive muscular dystrophy can cause creatine kinase to increase. 4. Thrombolytic therapy: reperfusion after thrombolytic therapy for myocardial infarction can cause increased creatine kinase activity, resulting in increased creatine kinase. 5. Surgery: cardiac surgery or non-cardiac surgery can cause increased creatine kinase, and the degree of elevation is related to the degree of muscle damage, the scope and duration of surgery. It is recommended to go to the hospital in time to get a clear diagnosis and treatment for high creatine kinase CK to avoid delaying the condition.