Patients with nephritis glomerular filtration rate of 43ml/min, accompanied by renal cancer, have the chance to be treated surgically, which still needs to be combined with the actual situation of the patient. As a kidney cancer patient, whether it is necessary to do surgery again also depends on whether there are indications for surgery, such as staging. If it is an early stage kidney cancer patient, there is a chance for surgery and surgery can be chosen; if it is an advanced stage patient, surgery is generally not recommended. When the patient’s glomerular filtration rate is 43ml/min, it indicates that the patient has serious renal insufficiency and the patient has already suffered from renal failure. Whether there are contraindications to surgery for this kind of patients with renal cancer or not, it is necessary for the professional doctors to evaluate the patient’s physical status in detail before deciding. It is recommended to go to regular hospitals for comprehensive evaluation of the condition, follow the doctor’s instruction to cooperate with the treatment, choose the appropriate treatment plan to improve the prognosis of the patient, so as to avoid delaying the condition.