A running calf pain refers to patellofemoral pain, mainly considering patellar tendonitis, tibiofibular periostitis and tibial tuberosity osteochondritis and other reasons. 1. patellar tendonitis: due to often do strenuous exercise or jumping, caused by the patellar tendon stop repeatedly pulling the occurrence of patellar tendon chronic aseptic inflammation, pain in the front of the calf on the side, aggravated by exertion, rest to alleviate, can be used externally with non-steroidal anti-inflammatory drugs, such as diclofenac diethylamide cream, etc. treatment. 2. Tibiofibular periostitis: due to frequent running and jumping or walking too much caused by tibiofibular periosteum between the occurrence of aseptic inflammation, manifested as localized swelling, pressure and pain, a running to meet the face of the bone pain, through rest, hot compresses, ultrashort-wave physiotherapy symptoms can be reduced. 3. Tibial tuberosity osteochondritis dissecans: mostly seen in 13 to 15 years old teenagers, because of the long-term large amount of sports and caused by the tibial tuberosity osteochondritis dissecans this kind of situation. Because this is a self-limiting disease, rest is the main focus, and if necessary, heat can be applied. Generally speaking, after adulthood, basically can be recovered and relieved. A running calf facing bone pain if often occurs, need to go to the hospital orthopedic examination to clarify the diagnosis and further treatment.