Autoimmune liver is also known as autoimmune liver disease, the transaminase does not come down mostly due to the failure to take targeted treatment, need to timely medication or surgical treatment. Autoimmune liver disease is a kind of chronic inflammation of the liver related to autoimmune ability, there is no complete cure and program, generally through drugs, dietary modification and other ways to stabilize the condition, such as transaminases do not come down the situation, most of the time consider that the patient does not get effective treatment, you need to consult a doctor in a timely manner under the guidance of the doctor’s treatment. Autoimmune liver disease treatment is mainly based on glucocorticoids, immunosuppressive drugs, such as prednisone, cyclosporine, azathioprine, etc., such as aminotransferases continue to rise, you need to use the compound glycyrrhizin, adenosylmethionine and other medications, once cirrhosis occurs, if necessary, can be considered to carry out liver transplantation surgery. Autoimmune liver disease aminotransferases do not come down we need to pay attention to, active treatment, adjust personal diet to improve.