The nipple blisters are mostly due to the friction of the nipple epidermis by clothing, resulting in local breakage to form blisters, which should pay attention to the choice of fabric soft, suitable size of underwear, to avoid prolonged friction stimulation. In addition some pathological factors such as nipple eczema, nippleitis, etc. can also lead to long blisters: 1, nipple eczema: generally manifested as unilateral or bilateral papules and blisters on the nipple, areola area, may be accompanied by itching, itching avoid scratching, to avoid aggravating the condition. In clinical treatment can be under the doctor’s advice local wet application of compound cypress liquid coating, skin health lotion to dry damp, detoxification, itching, cooling treatment; 2, nipple infection: mostly caused by bacterial infection, manifested as redness, swelling, itching and blisters in the nipple area, can be under the doctor’s guidance to use erythromycin ointment for treatment; 3, mammary gland hyperplasia: mammary gland hyperplasia appear increased secretions, resulting in duct opening is not The secretions and glands gather around the nipple opening, causing local blisters to form. If necessary, a biopsy should be performed to rule out the possibility of breast cancer. 4. Herpes virus infection: Herpes virus infection can also cause local blisters, which are usually accompanied by pain, and need to be treated with antiviral drugs. In addition, some women who are breastfeeding are also prone to blisters on their nipples, mostly due to excessive suction or improper breastfeeding posture, which can cause damage to the breasts and blisters.