A fissure between the vagina and anus may be caused by infection, etc. It can be treated by keeping the fissure clean, improving diet or medication (such as erythromycin). 1. Keep the fissure clean: once the patient finds a fissure between his vagina and anus, he needs to keep the fissure clean as much as possible. He can disinfect the fissure with povidone-iodine and change his clothes and pants diligently to keep the fissure clean, which will help the wound to heal. 2. Improve the diet: once the patient found his vagina and anus between the fissure need to try to eat a light diet, avoid eating spicy stimulating food, moderate consumption of food containing more fiber, to prevent constipation aggravate the condition, to help the fissure healing. 3. Medication: If the patient’s fissure is inflamed, it can be treated with topical erythromycin ointment, mupirocin ointment, etc., to promote the subsiding of the infection and the healing of the fissure. Once the patient found his vagina and anus between the fissure, you need to consult a doctor in time, improve the relevant examination after the targeted treatment and treatment. Another tip: If you need to use drugs need to be under the guidance of a doctor, do not blindly use drugs.