Acne around the mouth may be due to folliculitis, acne, can be improved through the use of topical drugs and oral medication, depending on the cause of the symptomatic treatment. 1. Folliculitis: Folliculitis is an inflammatory skin disease that occurs in the hair follicles and is associated with bacterial infections, which can lead to the symptoms of acne around the mouth, and can be treated with drugs such as mupirocin ointment and fusidic acid cream. 2. Acne: Acne is a chronic inflammatory disease that occurs in the sebaceous glands of the hair follicles, which can also lead to symptoms of acne around the mouth, and can be treated with medications such as adapalene gel, benzoyl peroxide gel, azelaic acid and other drugs, and oral minocycline, isotretinoin and other medications if necessary for treatment. It is recommended to consult a doctor in time to identify the cause and use medication under the guidance of the doctor.