Alternating left and right sciatic nerve pain can be treated through life modification, medication, surgery, etc. Alternating left and right sciatic nerve pain may be caused by lumbar disc herniation, pyriformis syndrome, etc. The treatment method needs to be chosen according to the cause of the disease. 1. Lumbar disc herniation: bed rest should be taken and appropriate activities on the ground should be carried out. You can choose to use diclofenac sodium extended-release tablets, meloxicam capsules, flupirtine maleate capsules and other drugs, but also simple interlaminar open nucleus pulposus removal, total laminectomy, intervertebral fusion and other surgical methods for treatment. 2. Piriformis syndrome: you can choose to use ibuprofen extended-release capsules, meloxicam capsules, tretinoin capsules and other drugs or hot compresses, freezing, electrocautery, ultrasound and other physical methods of treatment, in serious cases, should be timely for the pyriformis tendon cut off the laxative surgery, sciatic nerve outlet enlargement decompression surgery and other surgical methods for treatment. In the use of medication, the need to standardize the use of professional physicians under the guidance of unauthorized use of medication, in order to avoid adverse reactions, not conducive to the recovery of the condition.