Many patients with mental illness do not think they have a disease, clinically called this type of mental illness has no self-control, for these patients there are the following: First, it is recommended that the patient’s family send the patient to a psychiatric hospital for mandatory inpatient treatment, which is the best option and the best treatment plan. Second, if the patient does not admit that he or she is ill and is unwilling to take medication, there are currently in the clinic, for example, Vistone oral solution and other aqueous agents, colorless and tasteless, which the patient’s family can put inside the diet that the patient eats to help the patient with treatment. Third, there are long-acting injections in the clinic, such as paliperidone, also known as Rida long-acting injection, 1 month or 0.5 month injection once, which is also an effective way.