There are many reasons for coughing at 3 or 4 a.m., commonly associated with cough variant asthma, pharyngitis, gastroesophageal reflux disease and so on. 1. Cough variant asthma: a special type of asthma, may be affected by genetic and environmental factors, coughing in the early hours of the morning is often due to cold air stimulation caused by the main manifestation of irritating dry cough, no obvious wheezing, shortness of breath and other symptoms. 2. Pharyngitis: mostly seen in chronic pharyngitis, due to long-term stimulation of inflammation, patients often have a burning sensation in the throat, dryness, foreign body sensation, especially in the morning, the cough will be more obvious. 3. Gastroesophageal reflux disease (GERD): a chronic disease in which the contents of the stomach and duodenum reflux into the esophagus, resulting in a series of symptoms. Sleeping in a flat state, acidic reflux may reflux into the throat, irritating the throat and trachea, causing coughing, pharyngeal discomfort and other symptoms. Its can cause 3-4 am cough. Coughing at three or four in the morning can also be seen in other diseases, it is recommended to go to the hospital in a timely manner, to clarify the cause of the disease, under the guidance of the doctor for standardized treatment.