Spots on a man’s face may be caused by seborrheic keratosis, freckles, chloasma and other diseases. 1. Seborrheic keratosis: the cause of the disease is not yet clear, which may be caused by skin aging, heredity, gene mutation, ultraviolet radiation and other factors. Patients may have spots of different sizes on the face, with rough surface, usually without obvious clinical symptoms. 2. Freckles: may be caused by heredity, ultraviolet radiation and other factors. Freckles occur on the face, and the lesions are round, ovoid, irregular, light brown or dark brown, often with symmetrical distribution. 3. Chloasma: Its etiology is still unclear, and it may be caused by factors such as heredity, ultraviolet irradiation and changes in sex hormone level. The main symptom is yellow-brown pigmentation spots on the face, which are symmetrically distributed, aggravated by sunlight irradiation and may persist. There are many reasons that lead to spots on men’s faces, and patients are advised to go to the hospital and find out the causes of the disease.