Vitiligo is a common acquired pigment loss skin and mucous membrane disease, progressive vitiligo can be treated with phototherapy such as narrow-spectrum medium-wave ultraviolet light or 308nm excimer laser, and it is recommended to take medication at the same time. Vitiligo progressive stage can consider recolor treatment, such as can use phototherapy, such as narrow spectrum medium wave ultraviolet light or 308nm excimer laser. Phototherapy can induce melanocyte proliferation and synthesize more melanin, so as to get rid of the white spots. It is recommended to make a treatment plan according to the patient’s white spot area and the location of the disease. As vitiligo may be caused by autoimmune factors, you can also take oral or injectable glucocorticosteroids, usually using small to medium doses, while local application of hormones or immunosuppressants. Phototherapy is mostly combined with the use of photosensitizers combined treatment, currently often use narrow-spectrum medium-wave ultraviolet light, 308nm excimer light or laser irradiation treatment. Commonly used drugs include hormones (such as prednisone), topical calcium-modulated phosphatase inhibitors (such as tacrolimus ointment), and topical vitamin D3 derivatives (calcipotriol ointment). Note that phototherapy requires mastery of dosage, and improper use may lead to sunburn-like reactions or even induce skin cancer. It is recommended that patients go to the hospital for consultation and standardized treatment under the guidance of doctors.