Pentavalent vaccine is generally necessary to protect against diphtheria, pertussis, and many other diseases, and is recommended if there are no contraindications. Pentavalent vaccine is a combination of diphtheria, pertussis, tetanus, and Hib. It can prevent diseases such as meningitis, pericarditis, pneumonia, bacteremia, epiglottitis, poliomyelitis, and other diseases caused by diphtheria, pertussis, tetanus, and Hib. Pentavalent vaccine is generally recommended and is effective in preventing the above diseases. Contraindications to vaccination include: allergy to any of the components of DPT vaccine; encephalopathy, uncontrolled epilepsy and other progressive neurological lesions; fever and acute illness should be postponed. Some patients may experience symptoms such as pain and nodules at the injection site after receiving Pentavalent Vaccine, and a few patients may also experience adverse reactions such as fever, diarrhea, vomiting, loss of appetite, crying and drowsiness. Whether Pentavalent vaccine needs to be injected or not, it is recommended that patients take into account their own situation and ask their doctor for guidance. After vaccination, the local skin should be kept clean and clean, avoiding premature exposure to water or scratching the skin, so as to avoid secondary infection, which is not conducive to good health.