Quadrivalent HPV vaccine is suitable for ages between 9-45 years old. The quadrivalent HPV vaccine is usually administered between the ages of 9-45 years old, and should be delayed if you are preparing for pregnancy or are pregnant or breastfeeding. The quadrivalent vaccine covers HPV16 and HPV18, the two very high-risk types of cervical cancer, and also includes HPV6 and HPV11. HPV infection with low-risk types of HPV, HPV6 and HPV11, is prone to cause warts and other sexually transmitted diseases. Some systemic adverse reactions, such as headache, fever, diarrhea, nausea, vomiting, and hypersensitivity reactions, may occur after vaccination. Localized adverse reactions, such as erythema, pain, hard nodules. Therefore, it is necessary to observe the vaccine at the injection site for 30 minutes after injection.