Domestic rotavirus generally refers to domestically produced rotavirus vaccine, while imported rotavirus generally refers to imported rotavirus vaccine, the difference between the two is the different time of inoculation and the different storage time. However, there is not much difference between the two in terms of their effectiveness in preventing rotavirus. 1. Vaccination time: domestic rotavirus vaccine can be inoculated after 2 months of age for the first time, and then once a year can be inoculated, full four years of age can not be inoculated. Imported rotavirus vaccine is pentavalent rotavirus vaccine. The imported rotavirus vaccine, i.e. pentavalent rotavirus vaccine, needs to be vaccinated once at the age of 2, 4 and 6 months, with three doses in total, and the third dose needs to be finished before the age of 8 months at the latest. 2. Preservation time: Domestic rotavirus vaccines such as hepatitis B vaccine have a preservation time of about 10 years, while imported rotavirus vaccines such as hepatitis B vaccine have a preservation time of about 15 years, so the preservation time of imported rotavirus vaccines is longer than that of domestic ones. Rotavirus infection can easily cause dehydration, imported rotavirus vaccine is more expensive, but the preventive effect of domestic and imported rotavirus vaccines are similar, you can choose the right vaccine according to your own situation.