A wart on the testicle that is getting bigger and more painful may be the result of warts, or syphilis, genital herpes and other diseases. 1. Condyloma acuminatum: It is caused by human papillomavirus infection, and is usually found in the anus as well as the genital area skin. It is a very good idea to have warts on the skin, and they are accompanied by pain and itchiness. 2. Syphilis: is caused by syphilis spirochete infection, infectious, mainly through sexual contact, mother-to-child transmission, blood transmission. The main symptoms are skin rash, papules, pustules or flat warts. 3. Genital herpes: related to the infection of herpes simplex virus, occurring in the urogenital organs and the skin around the anus. The main manifestation is localized blisters, and accompanied by pain, itching and other symptoms. In the case of atypical or unrecognized genital herpes, there may be localized hard nodules or an inflammatory follicular reaction. The above phenomenon may also be caused by other factors, it is recommended that patients go to the regular hospital for timely consultation, as soon as possible targeted treatment, if the disease is contagious, should be prohibited during the treatment of coitus.