Perianal eczema is eczema that is confined to the perianal area, manifesting as erythema, papules or even blisters, mostly related to local humidity, and is more likely to occur in children or physiological women. The occurrence of perianal eczema is often related to local physiological characteristics, moist and sticky, clothing is not breathable when easily stuffy, urine and faeces and other filth is not cleaned thoroughly in time, fermentation decomposition for ammonia, easy to stimulate the skin induced dermatitis. These are the main factors that make small infants and menstruating females more susceptible. The prerequisite for treatment is to remove the above-mentioned triggers, such as changing diapers or sanitary napkins in a timely manner, cleaning the area with warm and cool water, and keeping the area dry and clean. Choose appropriate topical medication according to the characteristics of the rash, such as ellagic acid ointment (for diaper eczema) or zinc oxide ointment, or Denide ointment. Note that the perianal skin mucosa is thin and tender, and the drug is strongly absorbed, so the use of hormonal ointments should be particularly cautious, with a weak effect and short course of treatment. If there is local rupture, timely application of erythromycin ointment, etc., to prevent secondary continued infection. If necessary, topical cleaning with 0.1% potassium permanganate solution. The special site of perianal eczema makes treatment and care equally important, early detection, early treatment, not abusing drugs is the key to healing.