Calf pain occurs when sleeping, mainly due to the following reasons: First, due to excessive exercise the day before or long-term inactivity, resulting in poor blood circulation in the lower limbs and inducing pain in the calf area. Second, due to the stimulation of wind and cold at night, then induced muscle spasm, resulting in poor blood circulation, and even the occurrence of pain and leg stiffness and other uncomfortable symptoms. The pain is triggered by rheumatoid arthritis or rheumatoid arthritis. Four, due to lack of calcium in the body or diabetes, nephrotic syndrome, etc., induced pain in the calf area, after the occurrence of this situation can be localized hot compresses or massage to relieve the pain symptoms.